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Avandia ( Rosiglitazone ) is a member of the thiazolidinedione family of oral hypoglycemic agents used to improve glycemic control by increasing insulin sensitivity in muscle and adipose tissue and in ...


Peroxisome proliferator–activated receptors ( PPARs ) are ligand-activated nuclear transcription factors that modulate expression of a large number of genes. In the United States, therapeutic agent ...


GlaxoSmithKline ( GSK ) has informed HealthCare Professionals of recent safety data concerning Rosiglitazone-containing products, i.e., Avandia ( Rosiglitazone maleate ) tablets, Avandamet ( Rosiglita ...


Rosiglitazone ( Avandia ) is widely used to treat patients with type 2 diabetes mellitus, but its effect on cardiovascular morbidity and mortality has not been determined. Steven E Nissen and Kathy W ...


The thiazolidinedione Rosiglitazone ( Avandia ) is an insulin sensitizer that is indicated for use either as monotherapy or in combination with Metformin or a sulfonylurea in patients whose type 2 dia ...


The FDA ( Food and Drug Administration ) is aware of a potential safety issue related to Avandia ( Rosiglitazone ), a drug approved to treat type 2 diabetes. Safety data from controlled clinical tria ...


The FDA ( Food and Drug Administration ) is aware of a potential safety issue related to Rosiglitazone ( Avandia ). Safety data from a pooled analysis of controlled clinical trials have shown a signi ...


The FDA ( Food and Drug Administration ) announced that the manufacturer of Avandia ( Rosiglitazone ), a drug used to treat type 2 diabetes, has agreed to add new information to the existing boxed war ...


The FDA ( Food and Drug Administration ) announced manufacturers, GlaxoSmithKline ( GSK ) and Takeda, of glitazones approved to treat type 2 diabetes, have agreed to add a stronger warning on the risk ...


Rosiglitazone (Avandia, Avandamet ) and Pioglitazone ( Actos, Competact ) are treatments for patients with type 2 diabetes and belong to a class of drugs called thiazolidinediones ( also called glita ...


Thiazolidinediones include Rosiglitazone ( Avandia and Avandamet ) and Pioglitazone ( Actos ). These medicines act to increase insulin sensitivity and are widely prescribed to treat type II diabetes m ...


Long-term use of glitazones, oral diabetic drugs, doubles the risk of fractures in women with type 2 diabetes. The findings are published in the Canadian Medical Association Journal ( CMAJ ). In abso ...


Older adults who take Rosiglitazone ( Avandia ), a diabetes medication, appear to have a higher risk of death and heart failure than those taking the related medication Pioglitazone ( Actos ). In 1 ...


On September 23, 2010, the FDA ( Food and Drug Administration ) announced that it would restrict access to Rosiglitazone ( Avandia ) through use of a Risk Evaluation and Mitigation Strategy, or REMS.U ...