Drugs Xagena
Raptiva ( Efalizumab ) is an immunosuppressive, humanized monoclonal antibody indicated for treatment of adult patients with moderate to severe chronic plaque psoriasis who have failed to respond to, ...
Rituximab ( MabThera; US: Rituxan ) is a monoclonal antibody representing a glycosylated immunoglobulin indicated for the treatment of: - Non-Hodgkins lymphoma: in combination with chemotherapy fo ...
Healthcare professionals have previously been informed of the risk of hypertension-related adverse events associated with use of Etoricoxib ( Arcoxia ), and of the contraindication for use of Etoricox ...
European Medicines Agency ( EMEA ) has completed a review of Rimonabant ( Acomplia ) after concerns about its psychiatric safety. Thereview has found that the benefits of Rimonabant do not outweigh th ...
The Healthcare Professionals have been informed about new safety information regarding the occurrence of cardiac valvulopathy / fibrotic disorders for the following medicines: Cabaser ( Cabergol ...
Celgene, in agreement with the Committee for Medicinal Products for Human Use ( CHMP ) of the European Medicines Agency ( EMEA ) has informed Healthcare Professionals about the following new safety in ...
Eli Lilly has informed Healthcare Professionals of important safety information and changes to the prescribing information for Celance ( Pergolide ) prompted by reports of fibrotic reactions, includin ...
At the end of July 2008, two cases of progressive multifocal leukoencephalopathy ( PML ) were reported in patients with multiple sclerosis receiving Natalizumab ( Tysabri ) in the European post-market ...
The safety and maximum tolerated dose ( MTD ) of sunitinib malate( Sutent ) in combination with Bevacizumab ( Avastin ) has been assessed in patients with metastatic renal cell carcinoma ( mRCC ) in a ...
Novartis has informed Healthcare Professional on the safety of Exjade ( Deferasirox ), which is indicated for the treatment of chronic iron overload due to frequent blood transfusions, or when Desfer ...
Use of a class of medications for treating an enlarged prostate, known as 5-alpha reductase inhibitors, are not associated with an increased hip fracture risk. Benign prostatic hyperplasia ( BPH ) ...
Older adults who take Rosiglitazone ( Avandia ), a diabetes medication, appear to have a higher risk of death and heart failure than those taking the related medication Pioglitazone ( Actos ). In 1 ...
Because of a risk of serious hepatotoxicity with Nizoral ( Ketoconazole ), and the availability of other effective antifungal treatments, the Summary of Product Characteristics ( SmPC ) has been revis ...
Gilead has informed all healthcare professionals involved in the management of chronic hepatitis B on important renal safety information and recommendations in the current European Summary of Product ...
A recent assessment of adverse reactions associated with the use of Moxifloxacin ( Avelox ) resulted in the following information and recommendations: Treatment with Moxifloxacin is associated wi ...
In a clinical study ( study 400 ) the use of InductOs ( Dibotermin alfa ) in acute open tibia fractures, as an adjunct to standard of care ( SOC ), using reamed intramedullary nails, has resulted in a ...
Genzyme Europe BV has informed Healthcare Professional of six infection-related deaths, reported from a trial ( CALGB10101 ) in which previously untreated, symptomatic B-cell chronic lymphocytic leuke ...
Telbivudine ( Sebivo ) is a new nucleoside analogue that is indicated for treatment of chronic hepatitis B in adults with compensated liver disease and evidence of viral replication, persistently ele ...
In agreement with the EMEA ( European Medicines Agency ), F.Hoffmann-La Roche has informed HealthCare Professional of new safety information regarding CellCept ( Mycophenolate mofetil ). Isolated c ...
In conjunction with EU regulatory authorities, including the MHRA, Cephalon has informed Healthcare Professional of the following new warnings and safety information for Provigil ( Modafinil ) regardi ...
Pfizer has informed that it has updated the US product labeling for Exubera ( Insulin human ) Inhalation Powder to include a warning with safety information about lung carcinoma cases observed in pati ...
Pfizer has informed Healthcare Professional of updated prescribing advice for Atorvastatin ( Lipitor ). The new advice relates to interactions and the risk of haemorrhagic stroke in patients with rece ...
The treatment of patients with diabetes mellitus should be based, wherever possible, on the results of studies of substantial size and duration that measure outcomes that are meaningful to patients. ...
Long-term use of glitazones, oral diabetic drugs, doubles the risk of fractures in women with type 2 diabetes. The findings are published in the Canadian Medical Association Journal ( CMAJ ). In abso ...
Physicians should not be prescribing antibiotics to adults for the common rhinosinusitis infection, even if patients report symptoms lasting longer than 7-10 days. Upper respiratory tract infection ...
Nearly every child who receives an antipsychotic drug is first prescribed one of the second-generation, or atypical drugs, such as Olanzapine ( Zyprexa ) and Risperidone ( Risperdal ). However, there ...
A review of studies has concluded that, compared to older drugs for Parkinson disease, a newer class of medications called dopamine agonists might be better at preventing some of the disabling muscle ...
Anticholinergic drugs may cause older people to experience greater decline in their thinking skills than people not taking the drugs, according to research presented at the American Academy of Neurolo ...
A new pilot study by Researchers at Memorial Sloan-Kettering Cancer Center ( MSKCC ) found that breast cancer patients can be treated safely with a dose-dense regimen of standard chemotherapy agents a ...
On 18 March 2009, Bristol-Myers Squibb Pharma EEIG officially notified the Committee for Medicinal Products for Human Use ( CHMP ) that it wishes to withdraw its application for a marketing authorisat ...
Denosumab ( Prolia ) is a monoclonal antibody against receptor activator of nuclear factor-kappa B ligand ( RANKL ).The following safety issues associated with Denosumab exposure have been identified ...
The FDA ( Food and Drug Administration ) issued new information to health care professionals to alert them about an increased risk of suicidal thoughts and behaviors in patients who take drugs called ...
Tumor necrosis factor a ( TNF- alpha ) blockade has emerged as a useful therapy for collagen vascular diseases or graft-vs-host disease. Fungal infections complicating such therapy have been reported ...
The FDA ( Food and Drug Administration ) has approved Nexium ( Esomeprazole ) for short-term use in children ages 1-11 years for the treatment of gastroesophageal reflux disease ( GERD ). The agency ...
Biogen ldec and Elan have informed HealthCare Profesionals of new safety information regarding Tysabri ( Natalizumab ). The full Prescribing Information has been revised to add to the Warnings and P ...
Oral Terbinafine ( Lamisil ) is approved for the treatment of fungal infections of the nails and skin that are not responsive to topical therapy. ADRAC ( Adverse Drug Reactions Advisory Committee ) ...
Researchers have identified which variations of a specific gene determine a patients initial response to treatment with the anticoagulant drug Warfarin ( Coumadin ). Researchers found that the gene ...
Roche has informed HealthCare Professionals on recent update to the Tamiflu ( Oseltamivir ) package insert. The revisions to the product label are the result of recommendations made by the FDA Pedia ...
The FDA ( Food and Drug Administration ) is investigating a possible association between the use of Singulair ( Montelukast ) and behavior/mood changes, suicidality ( suicidal thinking and behavior ) ...
A study looked at the effects of taking a medication with anticholinergic properties on the annual change in thinking abilities of 870 Catholic nuns and clergy members who were an average of 75 years ...
Schizophrenia is a complex type of psychotic mental illness characterized by thoughts that are uncoupled from reality. Huge gains in the effective treatment of individuals with the disease began in th ...
Previous research on animal and physiological models suggest that antioxidant supplements have beneficial effects that may prolong life. Some observational studies also suggest that antioxidant supple ...
Amgen and Wyeth Pharmaceuticals have added a Boxed Warning to the Enbrel ( Etanercept ) US Prescribing Information to further strengthen and clarify information regarding the risk of infections, inclu ...
The CHMP, the scientific Committee of the European Medicines Agency ( EMEA ), adopted a negative opinion, recommending the refusal of the marketing authorisation for the medicinal product Ramelteon 4 ...
The FDA ( Food and Drug Administration ) has notified manufacturers of fluoroquinolone antimicrobial drugs that a Boxed Warning in the product labeling concerning the increased risk of tendinitis and ...
The FDA ( Food and Drug Administration ) has approved once-daily Seroquel XR ( Quetiapine fumarate ) Extended-Release Tablets for the acute treatment of the depressive episodes associated with bipolar ...
Patients treated for their prolonged seizures with the sedative Propofol ( Diprivan ) may be at high risk for complications and even death. New research showed that the use of Propofol as an antiep ...
On November 8, 2007, the Aranesp ( Darbepoetin alpha ) and Epogen / Procrit ( Epoetin alpha ) labeling were revised to describe the results of 6 studies showing increased mortality and more rapid tumo ...
The FDA ( Food and Drug Administration ) has approved additional changes to the Ortho Evra Contraceptive Transdermal Patch label to include the results of a new epidemiology study that found that user ...
The FDA ( Food and Drug Administration ) has approved Tysabri ( Natalizumab ) for the treatment of moderate-to-severe Crohn's disease in patients with evidence of inflammation who have had an inadequa ...
