Drugs Xagena
Roche has announced new Phase II efficacy data from the investigational compound GA101 ( RG 1759; Obinutuzumab ) in relapsed / refractory non-Hodgkin's lymphoma ( NHL ).GA101 is the first type II ...
The FDA ( Food and Drug Administration ) has announced that the Agency is recommending removing the breast cancer indication from the label for Avastin ( Bevacizumab ) because the drug has not been sh ...
A widely prescribed class of drugs is highly effective in reducing common bone fractures in people with osteoporosis, but an expert panel announced that these same drugs, when used long term, may be r ...
Provenge ( Sipuleucel-T ) is an autologous cellular immunotherapy designed to stimulate a patients own immune system against cancer. Provenge is manufactured in several steps. First the patients bl ...
Tolvaptan ( Samsca ) is an orally administered, nonpeptide, selective arginine vasopressin V(2) receptor antagonist that increases free water clearance, thereby correcting low serum sodium levels. ...
The high degree of selectivity of PLX4032 ( RG7204 ) enables substantial RAF/MEK/ERK pathway inhibition, which may be necessary to achieve significant tumor shrinkage and clinical response in patients ...
Findings from a new study show, compared to placebo, treatment with high-dose prescription Omega-3 fatty acids did not reduce the recurrence of symptomatic atrial fibrillation among patients with symp ...
An investigational drug, Anacetrapib, has raised HDL cholesterol by 138% and decreased LDL cholesterol by 40% without raising blood pressure. DEFINE ( Determining the EFficacy and Tolerability of C ...
The FDA ( Food and Drug Administration ) has approved Everolimus tablets ( Afinitor ) for the treatment of patients with advanced renal cell carcinoma after failure of treatment with Sunitinib or Sora ...
Osteoarthritis is the most common form of joint disease and the leading cause of pain and disability in the elderly. S-Adenosylmethionine ( SAMe; Samyr ) may be a viable treatment option but the evide ...
The FDA ( Food and Drug Administration ) issued a Follow-Up to the previous Early Communications issued in 2008, describing a potential increase in the risk of stroke, myocardial infarction, or death ...
Duloxetine is a balanced serotonin and noradrenaline reuptake inhibitor licensed for the treatment of major depressive disorders, urinary stress incontinence and the management of neuropathic pain ass ...
Cystic fibrosis is a genetic disorder with multiorgan effects. In a subgroup with pancreatic insufficiency malabsorption of the fat soluble vitamins ( A, D, E, K ) may occur. Vitamin D is involved in ...
Abatacept ( Orencia ) inhibits the co-stimulation of T cells and disrupts the inflammatory chain of events that leads to joint inflammation, pain, and damage in rheumatoid arthritis. Researchers at ...
A study has shown that Celecoxib ( Celebrex ) and other anti-inflammatory coxib medications may counter the positive effects of Acetylsalicylic acid ( Aspirin ) in preventing blood clots. The resea ...
In conjunction with EU regulatory authorities, including the MHRA, Cephalon has informed Healthcare Professional of the following new warnings and safety information for Provigil ( Modafinil ) re ...
In agreement with the EMEA ( European Medicines Agency ), F.Hoffmann-La Roche has informed HealthCare Professional of new safety information regarding CellCept ( Mycophenolate mofetil ). Isolated ...
Telbivudine ( Sebivo ) is a new nucleoside analogue that is indicated for treatment of chronic hepatitis B in adults with compensated liver disease and evidence of viral replication, persistently e ...
In a clinical study ( study 400 ) the use of InductOs ( Dibotermin alfa ) in acute open tibia fractures, as an adjunct to standard of care ( SOC ), using reamed intramedullary nails, has resulted in ...
Eli Lilly has informed Healthcare Professionals of important safety information and changes to the prescribing information for Celance ( Pergolide ) prompted by reports of fibrotic reactions, includ ...
Celgene, in agreement with the Committee for Medicinal Products for Human Use ( CHMP ) of the European Medicines Agency ( EMEA ) has informed Healthcare Professionals about the following new safety ...
The Healthcare Professionals have been informed about new safety information regarding the occurrence of cardiac valvulopathy / fibrotic disorders for the following medicines: Cabaser ( Caberg ...
Rituximab ( MabThera; US: Rituxan ) is a monoclonal antibody representing a glycosylated immunoglobulin indicated for the treatment of: - Non-Hodgkins lymphoma: in combination with ...
Taking regular Acetylsalicylic acid ( Aspirin ) and antioxidant supplements does not prevent myocardial infarctions even in high risk groups with diabetes and asymptomatic arterial disease, and Acet ...
The FDA ( Food and Drug Administration ) has completed its analysis of reports of suicidality ( suicidal behavior or ideation ) from placebo-controlled clinical trials of drugs used to treat epileps ...
The FDA ( Food and Drug Administration ) has approved the injectable drug Degarelix, the first new drug in several years for prostate cancer. Degarelix is intended to treat patients with advance ...
In the 2008, the FDA ( Food and Drug Administration ) has approved Bendamustine hydrochloride ( Treanda ), an intravenously administered alkylating agent, for the treatment of patients with indolent B ...
Bayer HealthCare and Genzyme, in collaboration with Health Canada, informed of important safety information regarding the use of MabCampath ( Alemtuzumab ) as consolidation therapy following combinati ...
Raptiva ( Efalizumab ) is an immunosuppressive, humanized monoclonal antibody indicated for treatment of adult patients with moderate to severe chronic plaque psoriasis who have failed to respond to, ...
Rituximab ( MabThera; US: Rituxan ) is a monoclonal antibody representing a glycosylated immunoglobulin indicated for the treatment of: - Non-Hodgkins lymphoma: in combination with chemotherapy fo ...
Healthcare professionals have previously been informed of the risk of hypertension-related adverse events associated with use of Etoricoxib ( Arcoxia ), and of the contraindication for use of Etoricox ...
European Medicines Agency ( EMEA ) has completed a review of Rimonabant ( Acomplia ) after concerns about its psychiatric safety. Thereview has found that the benefits of Rimonabant do not outweigh th ...
The Healthcare Professionals have been informed about new safety information regarding the occurrence of cardiac valvulopathy / fibrotic disorders for the following medicines: Cabaser ( Cabergol ...
Celgene, in agreement with the Committee for Medicinal Products for Human Use ( CHMP ) of the European Medicines Agency ( EMEA ) has informed Healthcare Professionals about the following new safety in ...
Eli Lilly has informed Healthcare Professionals of important safety information and changes to the prescribing information for Celance ( Pergolide ) prompted by reports of fibrotic reactions, includin ...
At the end of July 2008, two cases of progressive multifocal leukoencephalopathy ( PML ) were reported in patients with multiple sclerosis receiving Natalizumab ( Tysabri ) in the European post-market ...
The safety and maximum tolerated dose ( MTD ) of sunitinib malate( Sutent ) in combination with Bevacizumab ( Avastin ) has been assessed in patients with metastatic renal cell carcinoma ( mRCC ) in a ...
Novartis has informed Healthcare Professional on the safety of Exjade ( Deferasirox ), which is indicated for the treatment of chronic iron overload due to frequent blood transfusions, or when Desfer ...
Use of a class of medications for treating an enlarged prostate, known as 5-alpha reductase inhibitors, are not associated with an increased hip fracture risk. Benign prostatic hyperplasia ( BPH ) ...
Older adults who take Rosiglitazone ( Avandia ), a diabetes medication, appear to have a higher risk of death and heart failure than those taking the related medication Pioglitazone ( Actos ). In 1 ...
Because of a risk of serious hepatotoxicity with Nizoral ( Ketoconazole ), and the availability of other effective antifungal treatments, the Summary of Product Characteristics ( SmPC ) has been revis ...
Gilead has informed all healthcare professionals involved in the management of chronic hepatitis B on important renal safety information and recommendations in the current European Summary of Product ...
A recent assessment of adverse reactions associated with the use of Moxifloxacin ( Avelox ) resulted in the following information and recommendations: Treatment with Moxifloxacin is associated wi ...
In a clinical study ( study 400 ) the use of InductOs ( Dibotermin alfa ) in acute open tibia fractures, as an adjunct to standard of care ( SOC ), using reamed intramedullary nails, has resulted in a ...
Genzyme Europe BV has informed Healthcare Professional of six infection-related deaths, reported from a trial ( CALGB10101 ) in which previously untreated, symptomatic B-cell chronic lymphocytic leuke ...
Telbivudine ( Sebivo ) is a new nucleoside analogue that is indicated for treatment of chronic hepatitis B in adults with compensated liver disease and evidence of viral replication, persistently ele ...
In agreement with the EMEA ( European Medicines Agency ), F.Hoffmann-La Roche has informed HealthCare Professional of new safety information regarding CellCept ( Mycophenolate mofetil ). Isolated c ...
In conjunction with EU regulatory authorities, including the MHRA, Cephalon has informed Healthcare Professional of the following new warnings and safety information for Provigil ( Modafinil ) regardi ...
Pfizer has informed that it has updated the US product labeling for Exubera ( Insulin human ) Inhalation Powder to include a warning with safety information about lung carcinoma cases observed in pati ...
Pfizer has informed Healthcare Professional of updated prescribing advice for Atorvastatin ( Lipitor ). The new advice relates to interactions and the risk of haemorrhagic stroke in patients with rece ...
